Staff Contact: Shawn Billings or Kaylen Payne
It is well established that medications used to treat opioid use disorder are highly effective in preventing relapse into drug-taking, facilitating recovery and preventing overdoses. However, retention rates for these drugs are quite low, and 40% to 50% of patients treated with methadone or buprenorphine relapse within six months of starting treatment.
A randomized trial recently was conducted in Australia to compare patient-reported outcomes for daily sublingual buprenorphine treatment (tablets given under the tongue) versus a weekly or monthly injection of extended-release buprenorphine for OUD. The researchers found that the extended-release injection of buprenorphine was well-tolerated, acceptable to patients and produced generally more positive patient-reported outcomes, including overall patient satisfaction, effectiveness and convenience, compared to daily oral buprenorphine.