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COVID-19 Update | October 5, 2021



COVID-19 Update


  • COVID-19
  • Disease Management


coronavirus COVID-19

This report from the Missouri Hospital Association is designed to help you stay abreast of recent developments related to COVID-19.

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Booster Doses Dominate COVID-19 Vaccines In Missouri During First Week Of Expanded Authorization

Staff Contact: Mat Reidhead or Jackie Gatz

The Centers for Disease Control and Prevention now recommends certain individuals receive additional COVID-19 vaccines. A third dose is for immunocompromised individuals who may not have had a strong enough immune response to the primary vaccine series while a booster dose is an additional vaccination that is given to individuals as their protection weakens over time.

On Aug. 12, the U.S. Food and Drug Administration amended the emergency use authorization for both the Pfizer and Moderna COVID-19 vaccines for use of a third dose in solid organ transplant recipients or those who are diagnosed with conditions that are considered to have an equivalent level of immunocompromise. On Sept. 22, the FDA expanded the EUA of the Pfizer COVID-19 vaccine to authorize booster doses for certain individuals to include those over the age of 65, long-term care residents, individuals over the age of 18 with underlying medical conditions, or individuals who work or live in high-risk settings. The FDA Vaccines and Related Biological Products Advisory Committee is scheduled to meet next week to discuss booster doses for the Moderna and Johnson & Johnson COVID-19 vaccines.

The administration of third doses and booster shots has increased significantly in Missouri since the CDC expanded its interim guidance on eligibility for booster recipients on Sept. 24. Between Aug. 12 and Sept. 23, 40,740 third doses were administered statewide, presumably to immunocompromised Missourians and individuals seeking a third dose off-label. This accounted for 8% of the 508,282 total COVID-19 vaccine doses administered during the same period. Between Sept. 24 and Oct. 2, there were 62,231 third doses and booster shots administered, which accounted for 51% of the 122,022 total doses given in Missouri during the first nine days of expanded authorization.

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